PureStem® progenitor cells are novel human progenitor cells clonally derived from human embryonic stem cell lines. PureStem progenitors feature unique and phenotypically distinct embryonic progenitors representing early germ layers including ectoderm, mesoderm, neural Crest and endoderm. Progenitors express functional or gene expression differentiated phenotypes when cultured In PureStem Differentiation Kits; including mesenchymal epithelial myogenic and neurogenic phenotypes. Many PureStem progenitors generate unique differentiated cells and tissues by following known cell fates, including chondrogenic, osteogenic, endothelial and epithelial cell fates. PureStem progenitors are clonally pure and highly characterized with gene expression profiles both in their undifferentiated and differentiated fates. They do not express telomerase, and offer substantial proliferative capacity.