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PureStem® E72 BETATROPHIN+ Progenitor expresses the Mohawk homeobox gene (MKX), HAND2, TBX15, and the HOX genes: HOXA10, HOXD11 (implicated in forelimb development), but does not express the lateral plate mesoderm marker HOXB6 unless exposed to retinoic acid. Learn More

PureStem® EN7 Progenitor expresses neurofilament, medium polypeptide (NEFM), RGS1, tyrosine hydroxylase (TH), sarcosin (KBTBD10), gamma-aminobutyric acid (GABA) A receptor, beta 1 (GABRB1) (useful in screening for psychoactive drugs including those for the treatment of schizophrenia), the tight junction protein CLDN5, and MASP1. Learn More

PureStem® ES-1001 GDF11+ Progenitor expresses the NKD2, HAND2, TBX3, FOXF1, and the HOX genes: HOXA10 and the relatively distal HOX genes HOXB7 and HOXC8 as well as the hindlimb marker PITX1 (expressed in hindlimb, but not forelimb bud mesenchyme). Learn More

PureStem® ES-101 Progenitor expresses transthyretin (TTR), a marker of Blood Brain Barrier cells and choroid plexus making this progenitor valuable for research into diseases related to Cerebral Spinal Fluid or Alzheimer’s disease where defective choroid plexus function has been hypothesized. Learn More

PureStem® ES-139 Progenitor expresses tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18), heart and neural crest derivatives expressed 2 (HAND2), RNU2, GPR116, SPINK1, KRT86, GABRB1 (gamma-aminobutyric acid (GABA) A receptor, beta 1), and INS-IGF insulin- insulin-like growth factor 2. Learn More

PureStem® ES-154 Progenitor expresses the markers of intermediate mesodermal progenitors of the kidney (Lusis et al, 2010) including: Wilms tumor 1 gene (WT1), nephronectin (NPNT), TSHZ2, SIX1, and distal HOX gene expression HOXA4, B8, C8. Learn More

PureStem® ES-198 Progenitor expresses heparan sulfate 6-O-sulfotransferase 2 (HS6ST2), KIT, the ion channel SLC24A3, EPHA5, HEY2, and PLCH2. Learn More

Natural killer cell receptor proteins; expresses: cystatin SN (CST1), killer cell lectin-like receptor subfamily C, member 2 and 3 (KLRC2 and KLRC3). Expresses phosphodiesterase 5A, cGMP-specific (PDE5A), neuronal cell adhesion molecule (NRCAM), forkhead box G1 (FOXG1), and GATA binding protein 3 (GATA3). This progenitor does not express HOX genes. Learn More

PureStem® ES-209, Meso-prx/latp Progenitor expresses markers of intermediate mesoderm particularly resembling early renal progenitors, metanephric mesenchyme and S-shaped body markers (PAX2, PAX8, LHX1, HNF1B and JAG1). Learn More