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Cardiotoxicity


Cytiva® Plus Cardiomyocytes are derived from NIH Registered human Embryonic Stem Cells (hESC) and provide a biologically-relevant model for use in safety screening and risk assessment of compounds for cardiotoxic responses in drug discovery. Suitable for interrogation in multiparametic platforms such as high-content analysis (HCA) and multielectrode arrays (MEA), Cytiva Plus Cardiomyocytes form spontaneously beating monolayers when plated into microwell plates and exhibit appropriate morphology and electrophysiological responses when treated with known compounds.

  • Display expected multi-electrode arrays (MEA) waveform and performance characteristics.
  • Display expected pharmacological responses to compounds.
  • Cryopreserved for ease of use.
  • Ready to record direct from thaw after five to seven days incubation. No replating required.
  • Suitable for MEA, high-content analysis (HCA), calcium transient measurements, and manual patch clamping.

Interested in Cytiva Plus Cardiomyocytes? Request more information online »


Cytiva Plus Cardiomyocytes imaged on DeltaVision OMX™ imager

Figure 1. Cytiva Plus Cardiomyocytes imaged on DeltaVision OMX™ imager. Troponin I – green; α-actinin – red; nuclei – blue.


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  • Cytiva Plus Cardiomyocytes 3.5X10⁶ viable cells

    SKU: ES-7002
    Cytiva Plus Cardiomyocytes offered by ESI BIO are the highest quality cardiomyocytes derived from NIH-registered human embryonic stem cells. Learn More
    $1,339.00

  • Cytiva Plus Cardiomyocytes 1X10⁶ viable cells

    SKU: ES-7001
    Cytiva Plus Cardiomyocytes offered by ESI BIO are the highest quality cardiomyocytes derived from NIH-registered human embryonic stem cells. Learn More
    $386.00

  • Cytiva Cardiomyocytes 1.0X10⁵ viable cells

    SKU: ES-7003
    Cytiva Cardiomyocytes offered by ESI BIO are derived from NIH-registered human embryonic stem cells and provide a biologically relevant alternative to transfected cell models and primary cells for predictive toxicity testing and patch clamp testing. Cytiva Cardiomyocytes are not suitable for Multi-Electrode Array (MEA). For MEA applications, please request Cytiva Plus Cardiomyocytes. Learn More
    $335.00

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